MEETING HAS COMPLETED
Annual Meeting 2023-2024
January 16-17, 2024
RNCP, NIAID, NIH
IMPORTANT NOTICE:
As of late January 15, 2024, this hybrid meeting has changed to ALL VIRTUAL due to inclement weather conditions. A virtual link has been sent out to all attendees.
AGENDA
Day 1: Tuesday, January 16, 2024
8:30 am Check-in & A/V testing
9:00 am Welcome remarks from NIAID - Lanyn Taliaferro, PhD - NIAID CMCRC Project Scientist
CMCRC Program-Wide Cores
9:10 am Overview of Consortium-wide Coordinating Core: Yuji Zhang, PhD
9:20 am Overview of Opportunities Fund Management Core: Sally Amundson, PhD
9:30 am Q&A
Duke University CMCRC – Nelson Chao, PI (9:35-11:20am)
9:35 am Overview of Center & Project 1: Nelson Chao, MD – Duke University School of Medicine
CaMKK2 a novel target to mitigate radiation-induced injury of the hematopoietic system and the gastrointestinal tract.
10:00 am Project 2: Benny (Jun) Chen, MD – Duke University School of Medicine
Endothelial Cell-Derived Extracellular Vesicles for Mitigation of the Hematopoietic Acute Radiation Syndrome.
10:20 am Project 3: Jenny Ting, PhD – University of North Carolina School of Medicine
Innate immune receptor ligand and the microbiota as countermeasures for radiation
10:40 am Project 4: David Kirsch, MD, PhD – University of Toronto
Dissecting the Role of Revival Stem Cells in the Radiation-Induced Gastrointestinal
Syndrome to Define Targets for Mitigation.
11:00 am Discussion/Q&A - External Advisors† and Other Members
11:20 pm BREAK
11:30 am Gayle E Woloschak, PhD, FASTRO - Northwestern University
Studies on Radiological Exposures and Mitigation of Internal Exposures
12:25 am Q&A
12:30 pm LUNCH
Columbia University CMCRC – David Brenner, PI (1:30-3:00pm)
1:30 pm Overview of Center & Project 1: David Brenner, PhD – Columbia University
Overview of Center, and Project 1 (high throughput cytogenetics)
2:00 pm Project 2: Sally Amundson, PhD – Columbia University
Radiation biodosimetry using gene expression signatures
2:20 pm Project 3: Albert Fornace, MD presenting on behalf of Evagelia C Laiakis, PhD – Georgetown University
Rapid non-invasive radiation biodosimetry through metabolomics
2:40 pm Discussion by External Advisors† and Other Members: Q & A
3:00 pm BREAK
University of Maryland School of Medicine CMCRC – France Carrier, PI (3:15-5:05pm)
3:15 pm Overview of Center & Project 4: France Carrier, PhD – University of Maryland School of Medicine
Overview: INTERACT: Inter-collaborative Radiation Countermeasures Consortium Accomplishment and Vision Beyond 2025
Project 4 – “Characterizing senescence following Partial Body Irradiation”
3:45 pm Project 1: Christie Orschell, PhD – Indiana University School of Medicine
Development of prostaglandins as medical countermeasures for H-ARS and DEARE
4:05 pm Project 2: Sue Chin Lee (representing Gabor Tigyi, PhD – The University of Tennessee Health Science Center)
Advances in developing Radioprotectin-1
4:25 pm Project 3: Paul Okunieff, MD – University of Florida College of Medicine
Evaluation of basic fibroblast growth factor mimetic peptide as a mitigator of GI-ARS and H-ARS in a Wistar Rat Model
4:45 pm Discussion by External Advisors† and Other Members: Q & A
5:05 pm Wrap-up – Andrea Dicarlo, PhD (Director of RNCP)
5:15 pm Day One Adjourned
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Centers for Medical Countermeasures Against
Radiation Consortium (CMCRC)
Annual Meeting 2023-2024
January 16-17, 2024
RNCP, NIAID, NIH
Day 2: Wednesday, January 17, 2024
8:30 am Check-in & A/V testing
9:00 am NIAID Overview of CMCRC
9:15 am Dave T. Yeung, PhD – NIAID Chemical Countermeasures Research Program
An Introduction to the Chemical Countermeasures Research Program (CCRP)
9:30 -11:30 am - Collaborative Projects Presentations
Collaboration 1: Investigating Neutron-induced Lung Injury
9:30 am Guy Garty, PhD, Columbia University
France Carrier, PhD, University of Maryland
9:55 am Q&A
Collaboration 2: Evaluation of the Role of intestinal stem cell (ISC) subsets in promoting recovery from radiation injury underlying the acute gastrointestinal radiation syndrome (GI-ARS)
10:00 am Sue Chin Lee, PhD (representing Gabor Tigyi, PhD – The University of Tennessee Health Science Center)
Andrea Finholt-Daniel,PhD – Duke University School of Medicine
10:25 am Q&A
Collaboration 3: First studies determining the efficacy of countermeasures against radiation doses delivered in microseconds
10:30 am Brian Ponnaiya, PhD – Columbia University
10:55 am Q&A
11:00 am BREAK
Day 2 CMCRC Retreat - Closed Session
(PIs, Core Directors, NIAID Program Staff & External Advisors only)
11:10 am Feedback from EAB Advisors†
11:30 am Open Discussion (How to store the data and website content; future paths)
12:30 pm Wrap up of Closed Session
† Many thanks to the members of the CMCRC External Advisory Board for their valuable contributions to the consortium:
Jeffrey Buchsbaum, MD - NCI, NIH | Polly Chang, PhD - SRI |
Nicholas Dainiak, MD - Yale School of Medicine | Daniela Stricklin, PhD - FDA/CDRH |