NIH News of Note

·    A Checklist to Recount Study Design for Vertebrate Animal Research. Heed NIH's call to improve complete reporting of results of vertebrate animal and cephalopod experiments by using the Animal Research: Reporting of In Vivo Experiments checklist.

·    International Awards—Part II. Foreign Projects. Foreign research applications need to propose talent, resources, populations, or environmental conditions not available in the United States, e.g., access to a unique study population.

 

Save the Date - Summer 2023 RNCP Meeting

  • Advanced Technologies in Radiation Research Workshop. Hosted by the NIAID RNCP team, in partnership with colleagues from NCI, NASA and RITN. The hybrid meeting is scheduled for August 17-18, 2023, at the NIAID Conference Center  (5601 Fishers Lane, Rockville, MD 20892) with limited in-person attendance (virtual participation option available). The goal of the workshop is to provide an interactive forum for US Government funding agencies and researchers from private industry and academia to discuss innovative approaches in radiation research. Novel methods, including CRISPR, tissue chips, advanced computing, imaging modalities and other trending technologies can help accelerate the development of products to diagnose, mitigate, and treat radiation injuries. More details will be forthcoming. Please direct any pressing questions to Dr. Carmen Rios (carmen.rios@nih.gov) 

 

Training 

  • 2023 International Radiological Protection School (IRPS). To be held in person August 14-18 in Stockholm, Sweden. The International Radiological Protection School (IRPS) is developed and organized by the OECD Nuclear Energy Agency (NEA) in co-operation with the Swedish Radiation Safety Authority and the Centre for Radiation Protection Research of Stockholm University. Established in 2018, the course is designed to provide participants with a comprehensive understanding of the international radiological protection system, its application in diverse and emerging circumstances, and the latest developments based on new scientific knowledge and lessons learned. The program will provide participants with a thorough understanding of the international radiological protection system, how it is intended to be interpreted for application in diverse and emerging circumstances and how it is evolving based on new scientific knowledge and lessons learnt. The school will be driven by the same spirit of knowledge transfer as the previous editions: preparing tomorrow's leading experts in radiological protection by learning from today's experts. Comprehensive lectures and illustrative interactive case studies will be delivered by renowned experts in the multidisciplinary area of radiological protection. Deadline for applications: 15 April 2023.

 

FUNDING OPPORTUNITIES 

  • Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional). The NIH Research With Activities Related to Diversity (ReWARD) Program's overarching goal is to enhance the breadth and geographical location of research and research-related activities supported by NIH. The ReWARD program provides support for the health-related research of scientists who are making a significant contribution to Diversity, Equity, Inclusion, and Accessibility (DEIA) and who have no current NIH research project grant funding. The ReWARD program provides funding for both the scientific research and the DEIA activities of investigators. The grant will support scientific research in areas related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) and ongoing DEIA activities focused on enhancing diversity in the biomedical research enterprise within the United States and territories.

 

  • RFA-AG-24-019 Comparative Research (R01) Comparative Research on Determinants of Differences Among Human and Nonhuman Primate Species in Life Spans, Life Histories, and Other Aging-Related Outcomes, and Prospects for Translation. This Funding Opportunity Announcement (FOA) invites R01 applications proposing comparative studies of human and nonhuman primate species with differing life spans to identify factors whose cross-species variation may contribute to differences in species life span and health span, including, but not limited to, factors contributing to humans’ greater life span compared to other primates. Studies that involve primary in vivo or in vitro data generation and/or analyses of existing data or biospecimens are encouraged. Factors of interest include genetic, molecular, physiological, neurological, and behavioral traits. This FOA requests applications that propose studies to elucidate the relationship of such factors to primate species life span differences, and mechanisms that may mediate such relationships. These projects may also include research to identify potential human therapeutic targets and interventions that modulate mechanisms implicated by the comparative studies.
  • RFA-AG-24-020 Networking/Infrastructure Project for Research (R61/R33) Networking/Infrastructure Project for Research on Determinants of Differences Among Human and Nonhuman Primate Species in Life Spans, Life Histories, and Other Aging Related Outcomes, and Prospects for Translation. This Funding Opportunity Announcement (FOA) invites R61/R33 applications proposing to establish and conduct a networking and infrastructure project to enhance the development of comparative research on determinants of differences among human and nonhuman primate life spans, life histories, and other aging-related outcomes, and prospects for translating findings from this research into development of human interventions.
  • Notice of Special Interest (NOSI): Administrative Supplements to Initiate or Augment Outreach to and Inclusion of Sexual and Gender Minority (SGM) Populations. (NOT-CA-23-032) National Cancer Institute. This Notice of Special Interest (NOSI) describes an opportunity for supplemental funding to current grantees for studies that include sexual and gender minority (SGM) populations in cancer control research to enhance or accelerate the understanding of cancer-related health behaviors, care delivery, or health outcomes specific to the SGM population. Sexual and gender minority (SGM) people (including but not limited to, lesbian, gay, bisexual, asexual transgender, intersex, and non-binary people) are an underserved, understudied population. The goal of this initiative is to supplement existing awards to collect new data and/or analyze existing data through inclusion of and/or outreach to SGM individuals.

 

UPCOMING EVENTS

  • International Congress for Radiation Research (ICRR) Abstract  As you are preparing for the upcoming ICRR Meeting, here are the deadlines related to the abstract submission site: 
    • Abstract Submission Site Opens: Monday, February 13, 2023 
    • Abstract Submission Site Closes: Wednesday April 12, 2023
    • Late Breaking Abstract Submission Site Opens: Monday May 15, 2023
    • Late Breaking Abstract Submission Site Closes: Wednesday June 7, 2023

 

International Society of Radiation Epidemiology and Dosimetry. 

 

Hybrid meeting to be held May 16-18, 2023. The objectives of the meeting are to allow radiation researchers – engaged in research related to epidemiology, biology, and dosimetry – to discuss results of recent and ongoing studies of radiation effects in humans; to provide training opportunities for the next generation of radiation researchers; and to promote international collaborations in radiation research. Register here!

 

RECENT PUBLICATIONS

 

Article:Longitudinal multi-omic changes in the transcriptome and proteome of peripheral blood cells after a 4 Gy total body radiation dose to Rhesus macaques”

 

Drs. Shanaz Ghandhi, Igor Shuryak, Sally Amundson, David Brenner, Polly Chang, Helen Turner,  and colleagues show that a TBI 4 Gy dose in NHPs induces many cellular changes in the circulating peripheral blood, persisting up to 1 month after exposure, consistent with damage, death, and repopulation of blood cells. [BMC Genomics. 2023 Mar 21]

 

Shanaz A Ghandhi, Shad R Morton, Igor Shuryak, Younghyun Lee, Rajesh K Soni, Jay R Perrier, James Bakke, Janet Gahagan, Kim Bujold, Simon Authier, Sally A Amundson, David J Brenner, Denise Nishita, Polly Chang, Helen C Turner

 

Read more:

“Longitudinal multi-omic changes in the transcriptome and proteome of peripheral blood cells after a 4 Gy total body radiation dose to Rhesus macaques”

 

Job Opportunities

 

  • Post-Doctoral Position in Spatially Fractionated Radiation Therapy. Institute of Anatomy, University of Bern, Bern, Switzerland. Our research group is looking for a postdoctoral researcher with a background in immunology and/or genetics. We welcome applications from highly motivated, independent thinkers who can apply their knowledge to the field of radiation oncology with an emphasis on spatial fractionation and FLASH radiation therapy. We are looking for a candidate who can think outside the box and help us take our research to new heights.

 

 

  • Free Radical Biology and Metabolism in Cancer. University of Iowa College of Medicine, Department of Radiation Oncology, Iowa City, IA. The University of Iowa and Holden Comprehensive Cancer Center are seeking established faculty members to join the Free Radical and Radiation Biology Program (FRRBP) within the Department of Radiation Oncology. This position is an open rank tenure track faculty position. Responsibilities will include maintaining a successful extramurally supported research program centered around metabolism and free radical science in cancer, maintaining a record of scholarship on the national and international level, and teaching in the graduate and residency training programs.